The International Society for Computational Biology and the African Society for Bioinformatics and Computational Biology are pleased to once again join together to host the ISCB Africa ASBCB Conference on Bioinformatics in Kumasi, Ghana, November 11 – 15, 2019; conference workshops will be on November 14-15. This meeting constitutes the sixth joint meeting of ISCB and ASBCB, and the seventh conference of the ASBCB on Bioinformatics of Africa.